Advantage of precision metagenomics for urinary tract infection diagnostics

History shows that usual care testing is not the diagnostic solution for recurrent and complex UTI. This study supports that PM offers prospects to bridge the UTI diagnostic gap. This approach allows a workflow where laboratorians can qualify, quantify, and phenotypically classify pathogenicity more readily through bioinformatic platforms like Explify®, essentially providing dissected results across a broad array of input types and quantities for timely and accurate empiric UTI treatment. Moreover, PM offers potential for building effective diagnostic models beyond usual care testing in complex and coinfected UTI diseases. Future studies should assess the impact of PM-guided UTI management on clinical outcomes.